Christopher Wheat

  1. Du är här:
  2. Start
  3. Zoologiska institutionen
  4. Om oss
  5. Personal
  6. Christopher Wheat

Christopher Wheat


Ecological and Evolutionary Functional Genomics


Zoologiska institutionen: Populationsgenetik
08-16 40 20
Personlig webbplats:
08-15 95 22
Svante Arrheniusväg 18b
D 551
Stockholms universitet
Zoologiska institutionen: Populationsgenetik
106 91 Stockholm


In my group, research is focused on finding and studying the genetic variation causing performance and fitness variation in natural populations, as well as putting this into an evolutionary context. We use whatever tools we can to address a given quesition, from butterfly nets to genomes.



Kristin Franke, Isabell Karl, Tonatiuh Pena Centeno, Barbara Feldmeyer, Christian Lassek, Vicencio Oostra, Katharina Riedel, Mario Stanke, Christopher W. Wheat, Klaus Fischer. 2019. Effects of adult temperature on gene expression in a butterfly - identifying pathways associated with thermal acclimation. BMC Evolutionary Biology 19.

Pablo Stelbrink, Stefan Pinkert, Stefan Brunzel, Jeremy Kerr, Christopher W. Wheat, Roland Brandl, Dirk Zeuss. 2019. Colour lightness of butterfly assemblages across North America and Europe. Scientific Reports 9.

Jofre Carnicer, Constanti Stefanescu, Maria Vives-Ingla, Carlos Lopez, Sofia Cortizas, Christopher Wheat, Roger Vila, Joan Llusia, Josep Penuelas. 2019. Phenotypic biomarkers of climatic impacts on declining insect populations - A key role for decadal drought, thermal buffering and amplification effects and host plant dynamics. Journal of Animal Ecology 88: 376-391.

Sara Kurland, Christopher W. Wheat, Maria de la Paz Celorio Mancera, Verena E. Kutschera, Jason Hill, Anastasia Andersson, Carl-Johan Rubin, Leif Andersson, Nils Ryman, Linda Laikre. 2019. Exploring a Pool-seq-only approach for gaining population genomic insights in nonmodel species. Ecology and Evolution 9: 11448-11463.

Callum J. Macgregor, Chris D. Thomas, David B. Roy, Mark A. Beaumont, James R. Bell, Tom Brereton, Jon R. Bridle, Calvin Dytham, Richard Fox, Karl Gotthard, Ary A. Hoffmann, Geoff Martin, Ian Middlebrook, Sören Nylin, Philip J. Platts, Rita Rasteiro, Ilik J. Saccheri, Romain Villoutreix, Christopher W. Wheat, Jane K. Hill. 2019. Climate-induced phenology shifts linked to range expansions in species with multiple reproductive cycles per year. Nature Communications 10.

Olle Lindestad, Christopher W. Wheat, Sören Nylin, Karl Gotthard. 2019. Local adaptation of photoperiodic plasticity maintains life cycle variation within latitudes in a butterfly. Ecology 100.

Christina Hansen Wheat, Wouter van der Bijl, Hans Temrin. 2019. Dogs, but Not Wolves, Lose Their Sensitivity Toward Novelty With Age. Frontiers in Psychology 10.

Alyssa Woronik, Kalle Tunström, Michael W. Perry, Ramprasad Neethiraj, Constanti Stefanescu, Maria de la Paz Celorio-Mancera, Oskar Brattström, Jason Hill, Philipp Lehmann, Reijo Käkelä, Christopher W. Wheat. 2019. A transposable element insertion is associated with an alternative life history strategy. Nature Communications 10.

Jason Hill, Pasi Rastas, Emily A. Hornett, Ramprasad Neethiraj, Nathan Clark, Nathan Morehouse, Maria de la Paz Celorio-Mancera, Jofre Carnicer Cols, Heinrich Dircksen, Camille Meslin, Naomi Keehnen, Peter Pruisscher, Kristin Sikkink, Maria Vives, Heiko Vogel, Christer Wiklund, Alyssa Woronik, Carol L. Boggs, Sören Nylin, Christopher W. Wheat. 2019. Unprecedented reorganization of holocentric chromosomes provides insights into the enigma of lepidopteran chromosome evolution. Science Advances 5.

Marjo Saastamoinen, Greta Bocedi, Julien Cote, Delphine Legrand, Frederic Guillaume, Christopher W. Wheat, Emanuel A. Fronhofer, Cristina Garcia, Roslyn Henry, Arild Husby, Michel Baguette, Dries Bonte, Aurelie Coulon, Hanna Kokko, Erik Matthysen, Kristjan Niitepold, Etsuko Nonaka, Virginie M. Stevens, Justin M. J. Travis, Kathleen Donohue, James M. Bullock, Maria del Mar Delgado. 2018. Genetics of dispersal. Biological Reviews 93: 574-599.

Vicencio Oostra, Marjo Saastamoinen, Bas J. Zwaan, Christopher W. Wheat. 2018. Strong phenotypic plasticity limits potential for evolutionary responses to climate change. Nature Communications 9.

Alyssa Woronik, Constanti Stefanescu, Reijo Kakela, Christopher W. Wheat, Philipp Lehmann. 2018. Physiological differences between female limited, alternative life history strategies - The Alba phenotype in the butterfly Colias croceus. Journal of insect physiology 107: 257-264.

Sumitha Nallu, Jason A. Hill, Kristine Don, Carlos Sahagun, Wei Zhang, Camille Meslin, Emilie Snell-Rood, Nathan L. Clark, Nathan I. Morehouse, Joy Bergelson, Christopher W. Wheat, Marcus R. Kronforst. 2018. The molecular genetic basis of herbivory between butterflies and their host plants. Nature Ecology & Evolution 2: 1418-1427.

Naomi L. P. Keehnen, Jason Hill, Sören Nylin, Christopher W. Wheat. 2018. Microevolutionary selection dynamics acting on immune genes of the green-veined white butterfly, Pieris napi. Molecular Ecology 27: 2807-2822.

Christina Hansen Wheat, John Fitzpatrick, Ingrid Tapper, Hans Temrin. 2018. Wolf (Canis lupus) Hybrids Highlight the Importance of Human-Directed Play Behavior During Domestication of Dogs (Canis familiaris). Journal of comparative psychology (1983) 132: 373-381.

Peter Pruisscher, Sören Nylin, Karl Gotthard, Christopher W. Wheat. 2018. Genetic variation underlying local adaptation of diapause induction along a cline in a butterfly. Molecular Ecology 27: 3613-3626.

Mariana P. Braga, Paulo R. Guimarães Jr, Christopher W. Wheat, Sören Nylin, Niklas Janz. 2018. Unifying host-associated diversification processes using butterfly-plant networks. Nature Communications 9.

Sören Nylin, Salvatore Agosta, Staffan Bensch, Walter A. Boeger, Mariana P. Braga, Daniel R. Brooks, Matthew L. Forister, Peter A. Hambäck, Eric P. Hoberg, Tommi Nyman, Alexander Schäpers, Alycia L. Stigall, Christopher W. Wheat, Martin Österling, Niklas Janz. 2018. Embracing Colonizations - A New Paradigm for Species Association Dynamics. Trends in Ecology & Evolution 33: 4-14.

Philipp Lehmann, Peter Pruisscher, Vladimir Kostal, Martin Moos, Petr Simek, Sören Nylin, Rasmus Agren, Leif Varemo, Christer Wiklund, Christopher W. Wheat, Karl Gotthard. 2018. Metabolome dynamics of diapause in the butterfly Pieris napi - distinguishing maintenance, termination and post-diapause phases. Journal of Experimental Biology 221.

Alexander Schäpers, Hampus Petrén, Christopher W. Wheat, Christer Wiklund, Magne Friberg. 2017. Female fecundity variation affects reproducibility of experiments on host plant preference and acceptance in a phytophagous insect. Proceedings of the Royal Society of London, Series B, Biological Sciences 284.

Reuben W. Nowell, Ben Elsworth, Vicencio Oostra, Bas J. Zwaan, Christopher W. Wheat, Marjo Saastamoinen, Ilik J. Saccheri, Arjen E. Van't Hof, Bethany R. Wasik, Heidi Connahs, Muhammad L. Aslam, Sujai Kumar, Richard J. Challis, Antonia Monteiro, Paul M. Brakefield, Mark Blaxter. 2017. A high-coverage draft genome of the mycalesine butterfly Bicyclus anynana. GigaScience 6.

Aaron B. A. Shafer, Claire R. Peart, Sergio Tusso, Inbar Maayan, Alan Brelsford, Christopher W. Wheat, Jochen B. W. Wolf. 2017. Bioinformatic processing of RAD-seq data dramatically impacts downstream population genetic inference. Methods in Ecology and Evolution 8: 907-917.

Naomi L. P. Keehnen, Jens Rolff, Ulrich Theopold, Christopher W. Wheat. 2017. Insect Antimicrobial Defences - A Brief History, Recent Findings, Biases, and a Way Forward in Evolutionary Studies. Advances in Insect Physiology 52: 1-33.

Kishor Dhaygude, Kalevi Trontti, Jenni Paviala, Claire Morandin, Christopher Wheat, Liselotte Sundström, Heikki Helanterä. 2017. Transcriptome sequencing reveals high isoform diversity in the ant Formica exsecta. PeerJ 5.

Patrícia Pečnerová, Eleftheria Palkopoulou, Christopher W. Wheat, Pontus Skoglund, Sergey Vartanyan, Alexei Tikhonov, Pavel Nikolskiy, Johannes van der Plicht, David Díez-del-Molino, Love Dalén. 2017. Mitogenome evolution in the last surviving woolly mammoth population reveals neutral and functional consequences of small population size. Evolution Letters 1: 292-303.

Ramprasad Neethiraj, Emily A. Hornett, Jason A. Hill, Christopher W. Wheat. 2017. Investigating the genomic basis of discrete phenotypes using a Pool-Seq-only approach - New insights into the genetics underlying colour variation in diverse taxa. Molecular Ecology 26: 4990-5002.

Philipp Lehmann, Wouter Van der Bijl, Sören Nylin, Christopher W. Wheat, Karl Gotthard. 2017. Timing of diapause termination in relation to variation in winter climate. Physiological entomology (Print) 42: 232-238.

Peter Pruisscher, Helena Larsdotter-Mellström, Constantí Stefanescu, Sören Nylin, Christopher W. Wheat, Karl Gotthard. 2017. Sex-linked inheritance of diapause induction in the butterfly Pieris napi. Physiological entomology (Print) 42: 257-265.

Alyssa Woronik, Christopher W. Wheat. 2017. Advances in finding Alba - the locus affecting life history and color polymorphism in a Colias butterfly. Journal of Evolutionary Biology 30: 26-39.

Philipp Lehmann, Peter Pruisscher, Diana Posledovich, Mikael Carlsson, Reijo Käkelä, Patrik Tang, Sören Nylin, Christopher W. Wheat, Christer Wiklund, Karl Gotthard. 2016. Energy and lipid metabolism during direct and diapause development in a pierid butterfly. Journal of Experimental Biology 219: 3049-3060.

Aaron B. A. Shafer, Jochen B. W. Wolf, Paulo C. Alves, Linnea Bergström, Guy Colling, Love Dalén, Luc De Meester, Robert Ekblom, Simone Fior, Mehrdad Hajibabaei, A. Rus Hoezel, Jacob Hoglund, Evelyn L. Jensen, Michael Krützen, Anita J. Norman, E. Martin Österling, N. Joop Ouborg, John Piccolo, Craig R. Primmer, Floyd A. Reed, Marie Roumet, Jordi Salmona, Michael K. Schwartz, Gernot Segelbacher, Jens Thaulow, Mia Valtonen, Philippine Vergeer, Matthias Weissensteiner, Christopher W. Wheat, Carlese Vilà, Piotr Zieliński. 2016. Genomics in Conservation - Case Studies and Bridging the Gap between Data and Application Reply. Trends in Ecology & Evolution 31: 83-84.

Maria de la Paz Celorio-Mancera, Christopher W. Wheat, Mikael Huss, Francesco Vezzi, Ramprasad Neethiraj, Johan Reimegård, Sören Nylin, Niklas Janz. 2016. Evolutionary history of host use, rather than plant phylogeny, determines gene expression in a generalist butterfly. BMC Evolutionary Biology 16.

C. Morandin, K. Dhaygude, J. Paviala, K. Trontti, Christopher Wheat, H. Helanterä. 2015. Caste-biases in gene expression are specific to developmental stage in the ant Formica exsecta. Journal of Evolutionary Biology 28: 1705-1718.

Patrick P. Edger, Hanna M. Heidel-Fischer, Michael Bekaert, Jadranka Rota, Gernot Gloeckner, Adrian E. Platts, David G. Heckel, Joshua P. Der, Eric K. Wafula, Michelle Tang, Johannes A. Hofberger, Ann Smithson, Jocelyn C. Hall, Matthieu Blanchette, Thomas E. Bureau, Stephen I. Wright, Claude W. dePamphilis, M. Eric Schranz, Michael S. Barker, Gavin C. Conant, Niklas Wahlberg, Heiko Vogel, J. Chris Pires, Christopher W. Wheat. 2015. The butterfly plant arms-race escalated by gene and genome duplications. Proceedings of the National Academy of Sciences of the United States of America 112: 8362-8366.

Aaron B. A. Shafer, Jochen B. W. Wolf, Paulo C. Alves, Linnea Bergstrom, Michael W. Bruford, Ioana Brannstrom, Guy Colling, Love Dalen, Luc De Meester, Robert Ekblom, Katie D. Fawcett, Simone Fior, Mehrdad Hajibabaei, Jason A. Hill, A. Rus Hoezel, Jacob Hoglund, Evelyn L. Jensen, Johannes Krause, Torsten N. Kristensen, Michael Kruetzen, John K. McKay, Anita J. Norman, Rob Ogden, E. Martin Osterling, N. Joop Ouborg, John Piccolo, Danijela Popovic, Craig R. Primmer, Floyd A. Reed, Marie Roumet, Jordi Salmona, Tamara Schenekar, Michael K. Schwartz, Gernot Segelbacher, Helen Senn, Jens Thaulow, Mia Valtonen, Andrew Veale, Philippine Vergeer, Nagarjun Vijay, Caries Vila, Matthias Weissensteiner, Lovisa Wennerström, Christopher W. Wheat, Piotr Zielinski. 2015. Genomics and the challenging translation into conservation practice. Trends in Ecology & Evolution 30: 78-87.

Virpi Ahola, Rainer Lehtonen, Panu Somervuo, Leena Salmela, Patrik Koskinen, Pasi Rastas, Niko Valimaki, Lars Paulin, Jouni Kvist, Niklas Wahlberg, Jaakko Tanskanen, Emily A. Hornett, Laura C. Ferguson, Shiqi Luo, Zijuan Cao, Maaike A. de Jong, Anne Duplouy, Olli-Pekka Smolander, Heiko Vogel, Rajiv C. McCoy, Kui Qian, Wong Swee Chong, Qin Zhang, Freed Ahmad, Jani K. Haukka, Aruj Joshi, Jarkko Salojarvi, Christopher W. Wheat, Ewald Grosse-Wilde, Daniel Hughes, Riku Katainen, Esa Pitkanen, Johannes Ylinen, Robert M. Waterhouse, Mikko Turunen, Anna Vaharautio, Sami P. Ojanen, Alan H. Schulman, Minna Taipale, Daniel Lawson, Esko Ukkonen, Veli Makinen, Marian R. Goldsmith, Liisa Holm, Petri Auvinen, Mikko J. Frilander, Ilkka Hanski. 2014. The Glanville fritillary genome retains an ancient karyotype and reveals selective chromosomal fusions in Lepidoptera. Nature Communications 5: 4737.

Niklas Wahlberg, Jadranka Rota, Michael F. Braby, Naomi E. Pierce, Christopher W. Wheat. 2014. Revised systematics and higher classification of pierid butterflies (Lepidoptera - Pieridae) based on molecular data. Zoologica Scripta 43: 641-650.

Christopher W. Wheat, Jason Hill. 2014. Pgi - the ongoing saga of a candidate gene. Current Opinion in Insect Science 4: 42-47.

Niklas Wahlberg, Christopher W. Wheat, Carlos Pena. 2013. Timing and Patterns in the Taxonomic Diversification of Lepidoptera (Butterflies and Moths). PLoS ONE 8: e80875.

Christopher W. Wheat, Niklas Wahlberg. 2013. Critiquing blind dating - the dangers of over-confident date estimates in comparative genomics. Trends in Ecology & Evolution 28: 636-642.

Maria de la Paz Celorio-Mancera, Christopher W. Wheat, Heiko Vogel, Lina Söderlind, Niklas Janz, Sören Nylin. 2013. Mechanisms of macroevolution - polyphagous plasticity in butterfly larvae revealed by RNA-Seq. Molecular Ecology 22: 4884-4895.

Christopher W. Wheat, Niklas Wahlberg. 2013. Phylogenomic Insights into the Cambrian Explosion, the Colonization of Land and the Evolution of Flight in Arthropoda. Systematic Biology 62: 93-109.

Övrigt vetenskapligt

Alyssa Woronik, Akito Kawahara, Andrew Warren, Anton Chichvarkhin, Christopher Wheat. A phylogenetic analysis of butterflies in the genus Colias.

Alyssa Woronik, Ramprasad Neethiraj, Philipp Lehmann, de la Paz Celorio Mancera Maria, Constanti Stefanescu, Jason Hill, Reijo Käkelä, Oskar Brattstrom, Christopher Wheat. A transposable element insertion is associated with a female-limited, alternative life history strategy.

Alyssa Woronik, Constanti Stefanescu, Reijo Käkelä, Christopher Wheat, Philipp Lehmann. Physiological differences between female limited, alternative life history strategies: the Alba phenotype in the butterfly Colias croceus.

Ramprasad Neethiraj, Maria de la Paz Celorio-Mancera, Sören Nylin, Christopher Wheat. Investigating cis-regulatory variation within and between populations reveals significant enrichment of genes in central metabolism.

Ramprasad Neethiraj, Sören Nylin, Christopher Wheat. Holocentric chromosomes facilitate recombination and genetic variation in Lepidoptera.

Ramprasad Neethiraj, Peter Pruisscher, Naomi Pruisscher Keehnen, Alyssa Woronik, Karl Gotthard, Sören Nylin, Christopher Wheat. A dark melanic morph of Pieris napi shares its origins with other dark morphs of Lepidoptera.

Naomi Keehnen, Lisa Fors, Peter Järver, Anna-Lena Spetz, Sören Nylin, Ulrich Theopold, Christopher Wheat. Geographic variation in hemocyte diversity and phagocytic propensity shows a diffuse genomic signature in the green veined white butterfly.

Naomi L. P. Keehnen, Lucie Kučerova, Sören Nylin, Ulrich Theopold, Christopher W. Wheat. The consequences of surviving infection across the metamorphic boundary - tradeoff insights from RNAseq and life history measures.

Peter Pruisscher, Sören Nylin, Christopher Wheat, Karl Gotthard. A chromosomal block containing clock genes associates with variation in diapause induction.

Olle Lindestad, Sören Nylin, Christopher W Wheat, Karl Gotthard. Context-dependent candidate genes - a test of within-population genetic variation for photoperiodic plasticity.

Olle Lindestad, Sören Nylin, Christopher W. Wheat, Karl Gotthard. Analyzing the neutral and adaptive background of butterfly voltinism reveals structural variation in a core circadian gene.

Peter Pruisscher, Philipp Lehmann, Maria de la Paz Celorio-Mancera, Sören Nylin, Karl Gotthard, Christopher Wheat. Transcriptomic profiling of pupal diapause in the butterfly Pieris napi.